Clinical HBOT Consultation – Ann Arbor, MI

Our initial work up includes many of the same types of tests ordered by conventional physicians: blood sugar, electrolytes, liver function, thyroid, hormones, immune system markers, iron studies, and other standard blood tests. However, we also look deeper into specific markers of methylation, fatty acid status, oxidative stress, inflammation, cholesterol chemistry, and higher-level evaluations of hormones, thyroid, adrenal, and immune parameters.
We also work exclusively with labs that understand the financial aspects of being out-of-network with insurance and have payment options that limit out-of-pocket expenses for our patients related to insurance denials. Examples of blood labs our clinic uses include:
● Direct Health Labs (via LabCorp)● Genova Methylation Panel● Empire Labs Inc.

Our extensive array of GI diagnostics comprehensively evaluate gut ecology and the presence of opportunistic bacteria, invasive yeast, and parasites. These tests also provide valuable insights into metabolic digestive weaknesses and gut lining integrity issues (i.e., leaky gut), as well as allow us to differentiate inflammatory processes and the gut’s ability to digest and absorb nutrients from the foods consumed. Other tests evaluate urine and breath byproducts to identify bacterial overgrowth or pathogens that might be impacting your health. Examples of GI tests our clinic uses include:
● Genova Diagnostics, GI Effects (Stool)● Great Plains Laboratory, Comprehensive Stool Analysis (Stool)● Great Plains Laboratory, (MOAT) Microbial Organic Acid Test (Urine)● Genova, Intestinal Permeability (Urine)● BioHealth Laboratory, Small Intestinal Bacterial Overgrowth (SIBO) Breath Testing (Breath)

What are Nutrigenomics?
Nutrigenomics is the study of nutrients as it relates to gene expression. The software we use to translate genomics tests, including 23andMe, Ancestry, and many others, focuses on identifying molecular-level weaknesses in an individual’s genome.
Nutrigenomics has also been described as the influence of genetic variation on nutrients by correlating single nucleotide polymorphisms (or SNPs), for example MTHFR, with a nutrient’s (i.e., folic acid) absorption, metabolism, or biological effects. Therefore, nutrigenomics aims to optimize nutrition with respect to an individual’s specific weaknesses (Clinical Medicine).
For our clinic’s purposes, SNPs cross-referenced to medical testing of blood, urine, saliva, etc. is the heart of our Clinical Health and Genomics approach.
Below is an example report where -/- means no abnormal gene, +/- means an abnormal copy inherited from mother OR father, +/+ means an abnormal copy inherited from mother AND father. The full report provides information for thousands of critical metabolic steps related to everything from methylation-histamine to neurochemistry-hormone balance, and the list goes on extensively.
● SNP Report (Full Report)

Nutritional and organic acid testing is used to determine nutritional deficiencies associated with fatigue, metabolic impairments, mood and sleep problems, hormone dysregulations, toxin accumulation, cognitive impairment, and so on.
Standard blood tests ordered by conventional doctors evaluate for obvious health problems which may or may not represent the full picture. The following functional medicine tests look "more fully" at metabolized byproducts of toxins, neurotransmitters, hormones, amino acids, organic acids, fatty acids, nutrients, and antioxidants, providing crucial insights that can help outline the root cause of health imbalances related to presenting symptoms. Examples of this class of testing include:
● Genova Diagnostics, Metabolomics (Blood & Urine)● Great Plains Laboratory, (OAT) Organic Acid Test (Urine)● SpectraCell Laboratories, Micronutrient Test (Blood)

The final common pathway for ALL accumulated negative effects of physical, biological, and emotional stress is the hypothalamus, pituitary, adrenal, thyroid, gonadal-hormonal (HPAGT) axis. This key axis comprises an intricate network of controls and balances coordinating the human nervous system, with its “Fight or Flight” tendencies, to all aspects of hormonal regulation.
Regardless if one’s stress is caused by inflammation, infection, toxicity, or emotional events (past or present), or a combination of all of the above, it is the HPAGT axis that takes the brunt of the burden. Once this system can no longer compensate for the totality of stress endured. Neurochemical-hormone imbalances linked to depression, anxiety, pain, insomnia, hypoglycemia, PMS, and so on, is the ultimate consequence of too much stress for too long.
Our clinic uses a variety of testing strategies to determine the overall status of the HPAGT axis and neurochemistry and to create rehab protocols for the related fatigue; sugar cravings; pre-, post-, and peri-menopausal symptoms; loss of sex drive; PCOS; dysmenorrhea; mood problems; sleep problems; declining cognitive function; and the list goes on. Often this class of tests involves collecting timed saliva or urine samples to assess a wide spectrum of hormone and neurotransmitter data points.
Examples of hormones tested include progesterone, testosterone, DHEA, cortisol, melatonin, thyroid hormones, and several others. Urine neurotransmitter testing in combination with saliva hormones can be especially helpful when evaluating mood problems, anxiety, AD(H)D, insomnia, phobias, et cetera. Examples of this class of testing includes:
● NeuroLab/Sanesco Health, HPA Stress & Neurotransmitter Profile (Urine & Saliva)● Precision Analytical, DUTCH Adrenal-Hormone Profile (Urine)● DiagnosTechs Inc., Adrenal Stress Index-Flex 5 (Saliva)● ZRT Laboratories, Saliva Hormone Assessment (Saliva)● DBS Labs, Neurotransmitter Testing (Urine)

At NBW Medical Center we use a variety of tests to evaluate for chemical sensitivity and food/environmental intolerances. Some tests measure inflammatory markers and look indirectly at metabolic byproducts to assist in diagnosing sensitivities while others culture blood products, such as white blood cells, and challenge them directly under controlled laboratory conditions.
Our clinic also uses specific tests to identify gluten sensitivity related to celiac disease and other more “subclinical” gluten sensitivity problems such as gluten intolerance seems to correlate frequently with constitutionally weak individuals. Examples of tests we use in this case include:
● Cell Science Systems, ALCAT Food & Chemical Sensitivity Test (Blood)● ELISA/ACT Biotechnologies, Food Sensitivity Testing (Blood)

As compared to delayed sensitivity testing described above, allergy and immune tests, such as skin and blood allergy tests, evaluate for immediate reactions to foods and chemicals that are distinctly different. Such tests measure the direct release of histamine or the presence of allergen-specific IgE molecules resulting from allergen exposure.
Likewise, IgG or delayed mediated testing does not reveal true “allergies.” The two are distinct and different from each other. For allergy evaluation, we specifically use the following tests:
● Cyrex Laboratories, Array Testing (Blood & Urine)● Genova Diagnostics, IgE Food Antibodies (Blood)● Genova Diagnostics, IgE Environmental Antibodies (Blood)

In-home sleep diagnostics are an increasingly popular and convenient way to diagnose sleep apnea or other forms of disordered sleep NOT associated with brainwave abnormalities or restless leg syndrome (which require in-lab testing).
The reason this approach is becoming the new standard for insurance, doctors, and patients is that it is considered more of a “true test” of sleep, assessing multiple nights in a row in a comfortable and familiar setting. The units are portable and easy to use, and the test is self-administered, which also makes it more cost effective.
We use an in-home sleep diagnostic company that bills all commercial insurance, including Medicare. The test evaluates oxygen saturation and respiratory excursion, and uses a recorded microphone to evaluate for abnormal palatal noises to detect subtle and obvious apnea events. The test also distinguishes the difference between central (brain mediated) mechanisms versus obstructive mechanisms.
One of its most important utilities for our client base is that it will detect clinically relevant oxygen deprivation while sleeping, which tends to be correlated to many symptoms such as fatigue, hormone abnormalities, mood, high blood pressure, pain sensitivity, headaches, and a long list of other potential associations.
● In-Home Sleep Diagnostics (3-Night Sleep Study)

Under the guidance of Dr. Yvonne Berry, Natural Balance Wellness Medical Center developed a cutting-edge treatment and diagnosis approach for people suspected to be suffering from biotoxin illness associated with water damaged buildings (ie. Chronic Inflammatory Response Syndrome - CIRS) associated with mold toxicity. We use an array of evidence-based diagnostics to determine if exposure to mold biotoxin (past or present) is central to your health concerns in the form of CIRS,
● Quest Labs / LabCorp, Shoemaker Biotoxin, Innate Immunity and HLA Testing (Blood)● Shoemaker (VCS) Visual Contrast Testing (In-Office Vision Testing)● API-Staph Nasal Culture for MARCoNS Test (Nasal Swab)● Environmental Relative Moldiness Index (ERMI) Testing (Dust Sample)● HERTSMI-2 DNA-based MsqPCR Test for Mold (Dust Sample)

● Phase-Angle, Bioimpedance, Hydration Test● Brain Electrical Testing: High-resolution, Relational, Resonance-based, Electroencephalic Mirroring (HIRREM)